Studies

  • New Study Suggests Improved HPA Axis Function After TVAM Procedure

    Neuroendocrine Responses to Transvascular Autonomic Modulation: A Modified Balloon Angioplasty in Multiple Sclerosis Patients Authors: Arata M., Z. Sternberg Michael Arata, MD of Autonomic Specialists and Zohara Sternberg, PhD have published another study on Transvascular Autonomic Modulation (TVAM) in the journal, Hormone and Metabolic Research. The study found that TVAM, an innovative treatment that offers […]

  • Safety of Venous Transvascular Autonomic Modulation

    Safety of Venous Transvascular Autonomic Modulation Authors: Arata M. Purpose Venous Transvasular Autonomic Modulation (TVAM) has been recently described for patients with sympathetic autonomic nervous system (ANS) dysfunction. The hypothesized mechanism being balloon activation of the venous distention reflex. Herein we describe the feasibility and safety of this approach in the outpatient setting. Material and […]

  • Salivary Cortisol Assessment of Response Following TVAM

    Salivary Cortisol Assessment of Response Following TVAM Authors: Arata M., Debarge P. Introduction The autonomic nervous system interacts with the hypothalamic-pituitary-adrenal axis (HPA axis). Autonomic dysfunction can lead dysfunction of the HPA axis. Here we describe the effect of TVAM therapy on the HPA axis as assessed by salivary cortisol levels. Methods Ninety-six patients with […]

  • Study Finds Blood Pressure (BP) Normalization After Procedure

    A new study on BP response to jugular ballooning was published in Dec 2013 issue of Phlebology (The Royal Society of Medicine Journals). The study investigates the systolic and diastolic blood pressure responses to balloon angioplasty in a population of Multiple Sclerosis (MS) patients with autonomic system dysfunction. Read the full study here: http://phl.sagepub.com/content/early/2013/12/20/0268355513512824.full Blood […]

  • New TVAM Study Published in Journal of Endovascular Therapy

    A new study on Transvascular Autonomic Modulation (TVAM) was published in the June 2014 edition of the Journal of Endovascular Therapy. The study compares the efficacy of the TVAM procedure vs. traditional balloon angioplasty in improving cardiovascular autonomic nervous system (ANS) dysfunction in Multiple Sclerosis (MS) patients. Readthe full study here: http://jet.sagepub.com/content/21/3/417.abstract Transvascular Autonomic Modulation: […]

  • QSART Assessment of Venous Autonomic Modulation

    QSART Assessment of Venous Autonomic Modulation Authors: Arata M., Debarge P. Background Diagnostic tests used to assess autonomic nervous system (ANS) function such as heart rate variability (HRV) have been applied in MS and track with physical disability and disease progression. Sympathetic activity in particular correlates with MS disease activity which can be assessed by […]

  • Study Investigates Safety and Efficacy of TVAM Procedure

    A new study on TVAM (transvascular autonomic modulation) was published in the April 2014 edition of ACTA PHLEBOLOGICA (Edizioni Minerva Medica), a Journal on Phlebology. The study investigates the safety and efficacy of the TVAM procedure. Download the full study here: http://www.minervamedica.it/en/journals/acta-phlebologica/article.php?cod=R43Y2014N01A0019 Transvascular Autonomic Modulation, Initial Assessment of Safety Authors: Arata M., Debarge P. Institution: […]

  • Transvascular Autonomic Modulation: Novel Venous Therapy For Autonomic Dysfunction

    Authors: M. Arata, Z. Sternberg Background Chronic cerebrospinal venous insufficiency (CCSVI) has been described as a condition resulting from impaired CNS venous drainage. Venous balloon angioplasty (BA) has been performed as a treatment for CCSVI. Autonomic nervous system (ANS) dysfunction has been proposed as mechanism underlying the occurrence of CCSVI. We hypothesize that the BA […]

  • Venous Transvascular Autonomic Modulation (TVAM), Initial Assessment and Safety

    Authors: Michael A. Arata, M.D. Background Patients undergoing central venous angioplasty (CVA) have demonstrated improvement in autonomic parameters. We hypothesize that this results from stimulation of low pressure baroreceptors during balloon inflation. This report describes the assessment of the autonomic effect of CVA using HRV parameters. Further, the veins were treated independent of anatomic abnormality […]

  • Alterations in Hypothalamic Pituitary Adrenal Axis Following Central Venous Balloon Dilation

    Authors: Michael A. Arata, M.D., Zohara Sternberg, Ph.D., Steven Cen, Ph.D. Purpose Chronic cerebrospinal venous insufficiency (CCSVI) has been described as a condition resulting from impaired CNS venous drainage in multiple sclerosis (MS) patients. Venous balloon angioplasty (BA) has been performed as a treatment for CCSVI, although a direct link between venous obstruction and CCSVI […]

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